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dc.contributor.advisorScottgale, Gwenen_US
dc.contributor.authorBurroughs, Taylor
dc.creatorBurroughs, Tayloren_US
dc.date2021-11-24T14:05:37.000en_US
dc.date.accessioned2021-11-29T11:29:03Z
dc.date.available2021-11-29T11:29:03Z
dc.date.issued2017-04-01en_US
dc.date.submitted2017-09-20T12:36:06-07:00en_US
dc.identifierhonors_theses/129en_US
dc.identifier.urihttp://hdl.handle.net/20.500.13013/602en_US
dc.description.abstractT regulatory cells are part of the immune system and act to control and suppress immune responses. A small population or a population of T regulatory cells with impaired function has been associated with allergic and autoimmune diseases. Without suppression from these cells, immune dysfunction can become prevalent and lead to disease. Previous studies have shown that exposure to microbes and parasites such as Helminths can boost the T regulatory cell population. In developed countries, where microbial and parasitic exposure is diminished, allergies and autoimmune disorders are on the rise. In this review, scholarly articles and recent clinical trials were examined to see what therapies are currently being tested using T regulatory cells. One of the most favorable therapies is adoptive transfer of T regulatory cells. This therapy has had promising results in the early stages. Patients who received adoptive transfer therapy have had more alleviation of their disease than those in the control groups who received traditional treatment. Future studies need to be done to come to clear conclusions about the effectiveness of adoptive transfer, which would include a larger sample size of patients and longer follow up periods after therapy. By improving our understanding of adoptive transfer as a treatment, patients with these disorders can hopefully have an improved quality of life in the future.en_US
dc.titleThe Role Of T Regulatory Cells In Allergy And Autoimmune Disease And Potential Therapeutic Optionsen_US
dc.typeThesisen_US
dc.legacy.pubstatuspublisheden_US
dc.description.departmentBiologyen_US
dc.date.displayApr-17en_US
dc.type.degreeBachelor of Science (BS)en_US
dc.legacy.pubtitleHonors Thesesen_US
dc.legacy.identifierhttps://digitalcommons.salemstate.edu/cgi/viewcontent.cgi?article=1129&context=honors_theses&unstamped=1en_US
dc.legacy.identifieritemhttps://digitalcommons.salemstate.edu/honors_theses/129en_US
dc.legacy.identifierfilehttps://digitalcommons.salemstate.edu/context/honors_theses/article/1129/type/native/viewcontenten_US
dc.subject.keywordadoptive transferen_US
dc.subject.keywordallergiesen_US
dc.subject.keywordautoimmune diseaseen_US
dc.subject.keywordhygiene hypothesisen_US
dc.subject.keywordt regulatory cellsen_US


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