• Login
    View Item 
    •   Home
    • Student Scholarship
    • Honors Theses
    • View Item
    •   Home
    • Student Scholarship
    • Honors Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of SSDRCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Digital Repository Deposit Agreement

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    An Investigation Into The Role Of Gamma Oscillations In Alzheimer's Disease And Future Treatment Options

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Moge%20Serena%20thesis.docx
    Size:
    2.662Mb
    Format:
    Microsoft Word 2007
    DownloadPDF Variant
    Title
    An Investigation Into The Role Of Gamma Oscillations In Alzheimer's Disease And Future Treatment Options
    Author
    Moge, Serena
    Date
    May 2022
    Subject
    Alzheimer's disease
    dementia
    gamma oscillations
    brain waves
    amyloid-beta
    tau protein
    
    Metadata
    Show full item record
    URI
    http://hdl.handle.net/20.500.13013/2660
    Abstract
    Alzheimer’s disease (AD) is the most common form of dementia and involves the deterioration of memory and other important cognitive functions. Despite 1 in 3 seniors dying from AD or another form of dementia, there still remains no cure. An accumulation of amyloid-beta (Aβ) plaques and tau protein aggregates are what characterize AD. There have been medicines developed that target Aβ and tau protein in order to improve symptoms, but these can neither stop nor delay the progression of AD. Instead, most of the medicines available only aid in symptom control and patient comfort. Researchers have begun to search for new theories of pathogenesis, which may assist in creating new treatments that might cure this disease. One novel area of research in this field is the role of gamma oscillations. It is believed that a disruption in gamma brain waves could be a cause of the formation of Aβ and tau protein aggregation. Although changes in gamma wave activity have been linked to several neurodegenerative and neuropsychiatric disorders, treatments that restore gamma oscillations to their normal activity have not been investigated widely. The goal of this research is to investigate the current knowledge on AD pathogenesis and treatments, with special emphasis on the impact of gamma oscillations and the exploration of treatments that target restoration of gamma waves.
    Advisor
    Chen, Changqing
    Department
    Chemistry and Physics
    Degree
    Bachelor of Science (BS)
    Collections
    Chemistry and Physics Honors Theses
    Honors Theses

    entitlement

     
    DSpace software (copyright © 2002 - 2025)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.