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What is the role of citrullination in ALS?

Camille, Webb
Camille, Webb
Title
What is the role of citrullination in ALS?
Date
2023-02-17
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Abstract
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. Degeneration of motor neurons occurs because of toxic protein aggregation. Protein Citrullination (PC) is altered dynamically in the spinal cord during disease progression and accumulates in protein aggregates. This presentation aims to discuss what is currently known and uncover novel proteins that are citrullinated in ALS.
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